HORDB

ID: hor005608
Uniprot ID: P13684
Protein name: Prolevitide
Gene name: NA
Organism: Xenopus laevis (African clawed frog)
Family: Gastrin/cholecystokinin family
Source: animal
Expression: Expressed by the skin glands.
Disease: NA
Comments: NA
Taxonomy: Xenopus (subgenus), Xenopus (genus), Xenopodinae (subfamily), Pipidae (family), Pipoidea (superfamily), Anura (order), Batrachia (superorder), Amphibia (class), Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0006952 defense response; GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: MYKGIFLCVLFAVICANSLAKPSSDADEDNDEVERYVRGWASKIGQTLGKIAKVGLQGLMQPKREAMLRSAEAQGMIGTLTSKRIKQG
Length: 88
Propeptide: MYKGIFLCVLFAVICANSLAKPSSDADEDNDEVERYVRGWASKIGQTLGKIAKVGLQGLMQPKREAMLRSAEAQGMIGTLTSKRIKQG
Signal peptide: MYKGIFLCVLFAVICANSLA
Modification: T74 Pyrrolidone carboxylic acid;T87 Glutamine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-C0HKS3-F1.pdb

hor005608_AF2.pdb

hor005608_ESM.pdb

Mass:	1114223	Formula:	C419H693N119O125S6
Absent amino acids:	H	Common amino acids:	AGKL
pI:	9.71	Basic residues:	13
Polar residues:	24	Hydrophobic residues:	31
Hydrophobicity:	-16.02	Boman Index:	-12322
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	88.75
Instability Index:	2787.05	Extinction Coefficient cystines:	8605
Absorbance 280nm:	98.91